- A metabolomic analysis of sudden infant death syndrome (SIDS) cases identified 35 significant metabolite predictors, including ornithine and 5-hydroxylysine.
- The study involved 300 infants, with a racially diverse cohort.
- SIDS cases demonstrated a mean age difference of −37.4 days compared to controls, with a higher prevalence of bedsharing noted in SIDS cases.
- Key biological pathways implicated included nitrogen metabolism and lipid metabolism.
- Validation in independent cohorts is needed to refine the clinical relevance of the identified metabolite biomarkers and associated biological pathways.
Exploratory Metabolomic Study Identifies Potential SIDS Pathways
Conexiant
January 23, 2025
