- Some patients reported symptom return before the 3-month estradiol ring replacement period.
- 17 women used extra estrogen in the final weeks; three replaced the ring early.
- Review analyzed 31 patient charts from a private practice.
- Serum estradiol levels were inconsistently recorded, limiting hormone-symptom comparison.
- Lead author Rachel Rubin, MD, noted a disconnect between expected and real-world duration.
- Researchers recommended further studies and hormone monitoring to adjust replacement timing.
Is the Estradiol Ring Losing Strength Early?
Conexiant
October 23, 2025
