1. Biennial mammography starting at age 40 saved more lives than starting at 50.
2. Screening every two years balanced benefits and screening harms effectively.
3. Annual screening offered limited added benefit but more false positives.
4. “Randomized controlled trials establish the foundational scientific evidence,” the study stated.
5. Older data and modeling assumptions limited precision of mortality estimates.
6. Clinicians should guide patients in individualized screening decisions.

Source: Annals of Internal Medicine