1. Review graded 54 factors across 73 exposure–outcome pairs for neonatal mortality.
2. Probable risks: maternal age ≥35, maternal complications (hypertensive/hemorrhagic disorders, anemia), prior stillbirth, maternal death/morbidity, preterm birth, low birth weight, and breastfeeding started ≥24 hours.
3. Probable protections: any antenatal care and delivery in health facilities.
4. Scope/methods: 64 reviews (5 without meta-analysis); AMSTAR-2 appraisal; registered protocol (PROSPERO).
5. Caveats: substantial heterogeneity; inconsistent publication-bias checks; evidence largely from low- and middle-income settings, limiting generalizability.
6. Disclosures: no study funding; no author conflicts; data synthesized from published reviews.

Source: eClinicalMedicine