1. Adverse pregnancy outcomes were linked to an elevated risk of atrial fibrillation lasting up to 46 years postdelivery.
2. Preeclampsia, gestational diabetes, preterm delivery, and large-for-gestational-age infants were the strongest predictors of later atrial fibrillation (AF).
3. AF risk was highest within ten years postpartum for hypertensive and preterm deliveries but remained elevated for decades.
4. Adjusting for postpregnancy hypertension attenuated most associations, indicating chronic hypertension as a key pathway.
5. Women with adverse pregnancy histories warrant early and ongoing cardiovascular monitoring to prevent and detect AF.

Source: JAMA Cardiology