In a multicenter study of patients with drug-resistant mesial temporal lobe epilepsy, laser thermal therapy led to seizure freedom in over half of participants after two years, with low complication rates and improved quality of life.
Gabapentin use was associated with a 29% increased risk of dementia and an 85% increased risk of mild cognitive impairment within 10 years of pain diagnosis.
A study of older adults found that specific oral bacteria were linked to cognitive performance and genetic risk for Alzheimer’s, while other microbes showed stronger associations in people with mild cognitive impairment.
A study of over 24,000 patients identified four common diagnostic paths that lead to Alzheimer’s disease, with multi-step sequences posing higher risk than single conditions and showing reproducibility in a national validation cohort.
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A large cohort study comparing methadone and buprenorphine for opioid use disorder found no significant difference in reducing illicit opioid use, but methadone showed better treatment retention after one year.
A new international consensus identifies five gynecologic conditions commonly linked with interstitial cystitis/bladder pain syndrome, urging clinicians to adopt a multidisciplinary and trauma-informed approach to care.
Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.