Vertex Pharmaceuticals' non-opioid drug, suzetrigine, showed little difference versus a placebo in reducing pain for lumbosacral radiculopathy, prompting FDA review for treating moderate-to-severe acute pain.
Vertex Pharmaceuticals' non-opioid drug demonstrated pain reduction in patients with lumbosacral radiculopathy but fell short of investor expectations, signaling continued interest in non-opioid treatment amid the opioid epidemic.
In a large cohort study of 180,483 acetaminophen users aged 65 or older, researchers found that use was associated with a 36% increased risk of lower gastrointestinal bleeding.
"Unfortunately, when we reviewed the latest evidence, we found that taking vitamin D with or without calcium does not prevent falls or fractures in older adults."
A genetic analysis published in Neurology Genetics revealed significant shared genetic connections between migraine and various gastrointestinal disorders, suggesting avenues for targeted treatment through the CGRP pathway.
Expanded preoperative evaluations can reduce postoperative delirium by 23% in older adults, but frailty doubles the risk—are your patients screened effectively?
Explore innovative approaches, including mindfulness, team efficiency, and psilocybin therapy, to address clinician burnout and mental health challenges.