January 16, 2025

New XLH Guidelines Shift Primary Therapy to Burosumab

"Burosumab treatment normalized ALP serum levels in about 80% of both pediatric and adolescent cohorts, suggesting a substantial improvement of rickets in these patients," report authors of comprehensive new evidence-based recommendations for X-linked hypophosphatemia management.

Conexiant

January 15, 2025

Bertagnolli to Exit NIH Director Role

NIH director, Dr. Monica M. Bertagnolli, is stepping down after launching major initiatives in women's health and long COVID research, indicating optimism for their continuation under new leadership.

Conexiant

January 15, 2025

Study: SLE, SjD Show Higher Depression Than RA

"Ongoing monitoring, not only of disease-specific activity but also of mental health, is essential for ensuring optimal and holistic care of chronically ill patients."

Conexiant

January 13, 2025

Genetic Links Between MDD and Diseases

"Our findings confirmed the extensive and significant causal role of genetic predisposition to MDD in contributing to human disease phenotypes."

Conexiant

January 13, 2025

TSPO Binding Links to Mood Disturbances

TSPO binding correlates with stress-linked mood and suicidal ideation in MDD, but causality remains uncertain.

Conexiant

January 09, 2025

Advances in Chronic Migraine Treatment and Prevention

Recent research in JAMA provides significant advances in the treatment of chronic migraine and underscores the risks associated with medication overuse, emphasizing the potential of novel treatments.

Conexiant

January 02, 2025

Trio of Trials Track Early Migraine Drug Response

Day 1 efficacy data from 3 trials reveal atogepant's rapid impact in reducing migraine frequency, with functional improvements as early as week 1.

Conexiant

December 26, 2024

Study Links Dopamine Dysregulation to Chronic Pain

New research uncovers how the loss of JMJD3, a key histone demethylase, disrupts dopamine production and amplifies chronic inflammatory pain in mice, offering insights into potential therapeutic targets.

Conexiant

February 13, 2023

Virtual Reality Has Laid Descartes’ Theory of Mind-Body Dualism to Rest

A key concept for which 17th century philosopher René Descartes is remembered is that of mind-body dualism: the belief that the immaterial mind and the physical body are two entirely distinct entities made of contrasting substances.

Cedars-Sinai Pulse