In a long-term cohort study, researchers found that specific retinal changes—thinner photoreceptor layers and thicker retinal pigment epithelium—were linked to a higher risk of developing amyotrophic lateral sclerosis, suggesting potential noninvasive biomarkers for early detection.
Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.
A human fasting study found that prolonged water-only fasting raised inflammatory and platelet activation markers, reduced amyloid beta proteins, and altered lipid and glucose metabolism, with most changes reversing after refeeding.
A large European study found that people with COPD walk slower and have reduced gait performance compared to healthy adults, with impairments worsening as disease severity increases.
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New research reviewed dozens of studies and revealed that visual dysfunction, including retinal changes, may serve as early signs of neurodegenerative and neurodevelopmental diseases, offering a noninvasive pathway for earlier diagnosis and disease monitoring.
At the EULAR 2025 Congress, researchers reported that GLP-1 receptor agonists were linked to reduced opioid use, pain, and fatigue in fibromyalgia patients based on a large real-world analysis.
Dysregulated Ca²⁺ signaling due to ANO3 mutations impairs K⁺ channel activation in striatal neurons, offering new insights into the pathophysiology of dystonia.