"Up to 32% of incident dementia cases could be attributable to clinically significant audiometric hearing loss," revealing the potential impact of treating hearing impairment for dementia prevention in older adults.
An accelerated decline in BMI and waist circumference, along with fluctuating HDL levels, may signal early cognitive impairments up to a decade before dementia diagnosis, study finds.
"These findings suggest that interventions to improve diet and manage central obesity might be best targeted in middle to older age," concludes the Whitehall II cohort study showing how midlife metrics correlate with hippocampal connectivity and cognitive function at age 70.
"Readers should not have to infer what was probably done; they should be told explicitly." This principle drives the comprehensive CONSORT 2025 update, with its 7 new checklist items aimed at improving clinical trial transparency.