New SECRETO study reveals combined oral contraceptives increase cryptogenic ischemic stroke risk threefold in women aged 18 to 49, independent of other known risk factors.
An investigational Fas inhibitor demonstrated encouraging results in patients with geographic atrophy (GA) in a phase 1b clinical trial. In the study, eyes treated with ONL1204 (ONL Therapeutics) showed reductions in GA lesion growth at 6 months of up to 50% compared to sham-treated eyes after 2 injections spaced 3 months apart, and a 42% reduction in lesion growth compared to fellow untreated eyes after a single injection.
Retinal Physician
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Dilraj Grewal, MD, an associate professor of ophthalmology at the Duke Eye Center in Durham, North Carolina, and associate director of the Duke Reading Center, reviewed investigational therapies currently in late-stage clinical trials that may soon expand the treatment armamentarium for noninfectious uveitis during the Retina World Congress in Fort Lauderdale, Florida.
Mark Barakat, MD, provided an update on the PRISM clinical trial for 4D-150 (4DMT) for wet AMD at the Retina World Congress meeting in Fort Lauderdale.
Radiation retinopathy remains the leading cause of vision loss following plaque brachytherapy for choroidal melanoma. However, emerging research is changing the ways that ophthalmologists manage, or potentially prevent, this complication.