A cohort study found that patients with bedaquiline-resistant tuberculosis had delayed microbiologic recovery, higher rates of treatment failure, and reduced tuberculosis-free survival at 18 months compared with those with bedaquiline-susceptible disease.
From 2019 to 2021, U.S. emergency departments saw a 125.4% rise in synthetic opioid overdoses, highlighting shifting trends in hospital use related to opioids during and before the COVID-19 pandemic.
Patients from the MeninGene study contributed serum samples over 5 years, revealing that autoimmune processes rarely drive long-term cognitive problems after bacterial meningitis.
In a small sample, dog acquisition during the COVID-19 pandemic was linked to a brief rise in cheerfulness, followed by potential declines in well-being, with effects varying by caregiving role and measure.
Researchers examine the potential contribution of Chlamydia pneumoniae and SARS-CoV-2 infections to Alzheimer’s disease pathogenesis, focusing on neuroinflammatory mechanisms and genetic factors such as APOEε4.