A 6-week randomized trial showed that a daily kefir-based synbiotic supplement lowered several inflammation-related proteins and improved cholesterol levels more effectively than omega-3 or inulin alone. The synbiotic reduced IL-6, IFN-γ, and other immune markers, increased butyrate levels, and did not affect glucose or insulin measures. Researchers noted the need for larger, placebo-controlled studies to confirm these biochemical effects and assess long-term clinical relevance.
