1. Oral transition therapy for infective endocarditis shows similar outcomes to IV therapy.
2. Oral switch group had a 10% treatment failure rate vs. 20% for IV-only.
3. Patients on oral therapy spent a median of 59 days outside hospital.
4. Early transition to oral therapy (within 10 days) associated with higher failure rates.
5. Study analyzed 333 patients treated from 2016-2023.
6. 57% of IV-only patients were POET-eligible.
7. Outcomes applicable to a broader population than previously documented.

Source: Clinical Infectious Diseases