Low-dose oral minoxidil showed comparable effectiveness to 5% topical minoxidil in treating female-pattern hair loss, with mild adverse effects such as hypertrichosis and peripheral edema. Topical minoxidil remains the only FDA-approved option for women, while oral use is off-label. Adjunctive treatments like microneedling and platelet-rich plasma may enhance results, though evidence is limited. Diagnosis is clinical and supported by dermoscopy or biopsy. The review highlighted individualized treatment, early intervention, and regular follow-up as key to managing hair loss in women.

Source: The New England Journal of Medicine