- Living network meta-analysis evaluates 39 drug regimens for hidradenitis suppurativa.
- Data from 25 randomized trials with 5,767 participants.
- Primary measure: Hidradenitis Suppurativa Clinical Response (HiSCR).
- Sonelokimab showed highest effectiveness.
- Discontinuation due to adverse events were relatively low.
- No significant superiority of new agents over adalimumab was noted.
- Small sample sizes hinder definitive outcomes.
- Larger trials needed for conclusive efficacy and safety assessments.
Source: JAMA Dermatology