The study examined 54 patients with alopecia areata on Janus kinase inhibitors (JAKi) therapy, revealing that 53.7% developed acne during treatment. Patients with a history of acne had nearly six times the odds of developing acne during treatment compared with those without prior acne, regardless of acne status at treatment initiation. Most acne cases began early in treatment, and the severity varied, with over half of patients pursuing treatment with over-the-counter or prescription products. The findings emphasize the importance of assessing acne history before starting JAKi therapy for alopecia areata.

Source: Science Direct