1. 53.7% of patients with alopecia areata on JAKi therapy developed acne during treatment.
2. Patients with a history of acne had nearly six times the odds of developing acne during treatment compared with those without prior acne.
3. Most acne cases began early in treatment, and the severity varied.
4. Over half of patients pursued treatment with over-the-counter or prescription products
5. .Awareness of acne as a potential adverse effect may inform counseling and management strategies for JAKi therapy.
6. The study did not require IRB approval and was based on patient-reported outcomes.
7. Further research may clarify the biological mechanisms and long-term effects of JAKi-associated acne.

Source: Science Direct