1. Distinct biological pathways identified for nevus-associated vs de novo melanoma.
2. High mole count significantly increases the risk for nevus-associated melanoma.
3. 38,801 adults studied over 11.4 years.
4. Nevus-associated melanomas diagnosed younger with thinner tumors.
5. Cumulative sun exposure linked to both melanoma types.
6. Males more affected by nevus-associated melanoma.
7. Study highlights the importance of genetic predisposition.

Source: JAMA Dermatology