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Conexiant chevron_right Dermatology chevron_right Is Skin Thicker with Vitamin C
From the Journals

Is Skin Thicker with Vitamin C?

Vitamin C may help thicken human skin by epigenetically activating genes involved in cell growth, according to new research using a lab-grown human skin model. The study found that vitamin C, or L-ascorbic acid, promotes epidermal proliferation by modifying gene activity through DNA demethylation.

Conexiant
Full Article Summary Notecard
  1. Developed a 3D human epidermal model.
  2. Treated with vitamin C (0.1 mM and 1.0 mM).
  3. Increased epidermal thickness and cell proliferation.
  4. Changes in DNA methylation observed.
  5. 393 genes differentially expressed.
  6. Main effect is proliferation, not differentiation.
  7. Potential for age-related skin health therapies.
  8. Further study of protein expression needed.

Source: Journal of Investigative Dermatology

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