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Conexiant chevron_right Dermatology chevron_right Benzene Formation in Benzoyl Peroxide Formulations Role in
From the Journals

Benzene Formation in Benzoyl Peroxide: Formulation’s Role

Researchers found that benzene formation in benzoyl peroxide products is influenced by formulation factors, with hot processing increasing levels and antioxidants reducing them.

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A recent study published in JAMA Dermatology evaluated the role of formulation in benzene formation within benzoyl peroxide products. Led by John S. Barbieri, the researchers analyzed 111 benzoyl peroxide-containing products to assess the influence of formulation characteristics on benzene concentrations. The study findings suggested that formulation variables, such as excipient selection and temperature control during manufacturing, have a significant impact on benzene formation in benzoyl peroxide products. Further prospective studies are recommended to confirm these findings and assess the safety of over-the-counter benzoyl peroxide products.

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