A national analysis of 71,915 US census tracts found that neighborhoods with the highest structural-racism exposure had nearly double the prevalence of stroke, diabetes, obesity, smoking, and physical inactivity compared with the lowest-exposure tracts. Using the Structural Racism Effect Index across nine domains, researchers showed these associations persisted even after adjusting for demographics, health care access, and regional factors. The steepest disparities were tied to education and income-poverty domains. Patterns varied by neighborhood racial composition, with obesity highest in predominantly Black neighborhoods and diabetes in Hispanic or Latino neighborhoods. High-exposure areas were most concentrated in the South.