- Higher plasma levels of butyrate and isobutyrate may serve as early biomarkers of type 2 diabetes risk.
- The study followed 2241 adults without diabetes over a median 7-year period.
- SCFAs were positively associated with dietary intake of high-fiber foods.
- Circulating SCFAs were linked to dietary intake of fruits, vegetables, legumes, whole grains, and potatoes.
- Neither high-fiber consumption nor adherence to a a Mediterranean diet independently predicted incident T2D in the overall cohort.
Source: BMC Medicine