- Retrospective study on 4.6 million adults aged 50 years and younger.
- Cannabis users at higher risk of myocardial infarction and other major adverse cardiovascular events.
- Cannabis use is potentially linked to endothelial dysfunction, proinflammatory cytokine release, and oxidative stress.
- Study limitations include a lack of detailed cannabis consumption data and potential misclassification.
- Cannabis use may be an independent cardiovascular risk factor, even in young adults without traditional risk factors.
Source: JACC: Advances
