- Enhancement of peroxisome proliferator-activated receptor gamma (PPARG) is associated with a lower risk of diabetic retinopathy.
- Traditional lipid traits did not show a significant causal relationship with full-course diabetic retinopathy.
- PPARG displayed a protective effect against type 2 diabetes. Its protective effect on diabetic retinopathy was largely mediated by glucose control.
- PPARG is a promising candidate drug target for full-course diabetic retinopathy.
Source: British Journal of Ophthalmology
